Kanna

Sceletium tortuosum

A South African succulent traditionally chewed by the San people for mood elevation and stress relief. Contains mesembrine, a natural SSRI-like compound.

Safety Profile

Contraindications

NOT with SSRIs, MAOIs, or psychiatric medications. Depression requiring medical treatment.

Interactions

CRITICAL: May cause serotonin syndrome with SSRIs, SNRIs, MAOIs, and other serotonergic drugs.

Side Effects

Headache, nausea, mild euphoria. Appetite suppression.