Madagascar Periwinkle

Catharanthus roseus

Family: Apocynaceae Evidence: A extract

Toxic herb used to treat chronic lymphocytic leukemia, Hodgkin's disease, and acute lymphocytic leukemia. Source of vincristine and vinblastine.

Safety Profile

PregnancyUnsafe
BreastfeedingUnsafe
PediatricNot Recommended

Contraindications

Pregnancy, lactation, bone marrow suppression

Interactions

Interacts with CYP3A4 substrates, other chemotherapy agents

Side Effects

Nausea, vomiting, hair loss, bone marrow suppression, peripheral neuropathy

Surgery: Must inform surgeon; hematological monitoring required
Liver: Hepatotoxic
Kidney: Insufficient data
Allergy: Insufficient data
This information is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before using any herbal product.