Manaca Root

Brunfelsia uniflora

Family: Solanaceae Evidence: T tincturedecoction

Brazilian traditional remedy for arthritis, rheumatism, and syphilis. Root contains brunfelsamidine and scopoletin. Used by Amazonian tribes as ritual purgative. CAUTION: All parts contain toxic brunfelsamidine — narrow therapeutic window.

Safety Profile

PregnancyUnsafe
BreastfeedingUnsafe
PediatricNot Recommended

Contraindications

Pregnancy. CNS conditions. Narrow therapeutic index — TOXIC in excess.

Interactions

Sedatives, anticholinergics.

Side Effects

Tremors, excessive salivation, seizures in overdose. Nausea.

Allergy: Nightshade sensitivity.
This information is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before using any herbal product.