Crocus sativus
The world's most expensive spice, studied for mood support, with emerging evidence comparable to fluoxetine for mild-moderate depression.
Pregnancy in medicinal doses (culinary amounts are safe). Bipolar disorder.
May interact with SSRIs, blood thinners, and blood pressure medications.
Dry mouth, drowsiness, headache, nausea. TOXIC in very high doses (>5g).
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