Mitragyna stipulosa
West and Central African tree related to kratom (M. speciosa) but with distinct alkaloid profile. Used in Ghanaian and Nigerian traditional medicine for malaria, pain, and hypertension. Contains rhynchophylline and mitraphylline rather than mitragynine.
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Sedatives, opioids, antihypertensives.
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Sedation, GI upset. Limited safety data.
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