Perimenopause

Mood changes — perimenopause

Perimenopausal depression and anxiety have a real hormonal basis. Women with past postpartum depression or severe PMS are especially susceptible. This is not "just in your head" — it is neurochemistry shifting.

Key points

  • Ashwagandha + holy basil address the stress-axis underpinning
  • St John's Wort has good evidence but many drug interactions — review all meds
  • SSRIs and hormone therapy are both legitimate medical options; not failure to ask for them
  • Severe perimenopausal depression warrants medical-level care, not just herbs
  • Strength training + strength-social connection are both researched anti-depressants

Lifestyle & diet

Weight training 2-3× weekly, omega-3s (EPA-predominant 1-2 g/day), morning bright light, therapy or coaching tailored to this transition, protein at breakfast.

When to see a clinician

Suicidal ideation, inability to function, severe persistent depression — seek immediate care. This is a medical condition, not a character flaw.